The Effect of X-Ray Radiation to IL-10 Levels in Secretome Mesenchymal Stem Cells Cosmeceutical Product

  • Arini Dewi Antari Department of Pathological Anatomy, Medical Faculty, Sultan Agung Islamic University (UNISSULA), Semarang,  Indonesia
  • Shabrina Syifa Ghaissani Graduate School of Biology, Department of Biology, Faculty of Science and Data Analytics, Institute Technology of Sepuluh Nopember, Surabaya, East Java, Indonesia
  • Salindri Prawitasari Stem Cell and Cancer Research (SCCR) Indonesia, Semarang, Indonesia
  • Erlina Haryono Stem Cell and Cancer Research (SCCR) Indonesia, Semarang, Indonesia
  • Resanti Adityani Stem Cell and Cancer Research (SCCR) Indonesia, Semarang, Indonesia
Keywords: Xray, secretome, IL-10, ELISA, Cosmeceutical Product

Abstract

Background: X-ray radiation has been widely used in the pharmaceutical industry because it regenerates and repairs damaged tissues. Objective: In this study, we evaluate the effect of X-ray radiation on the secretome cosmeutical product. Methods: We conducted interleukin 10 (IL-10) analysis by ELISA in each product sample after exposure to X-ray radiation. Results: The levels of IL-10 in each sample were significantly lower than those in the control samples. Moreover, the level of IL-10 in the product samples was significantly higher than that of the control sample. Conclusion: In conclusion, exposure to radiation during shipping or storage of skin care products can potentially damage the proteins in the products by inducing the production of reactive oxygen species (ROS) and decreasing the treatment effectiveness.

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Published
2023-09-20
How to Cite
Antari, A. D., Ghaissani, S. S., Prawitasari, S., Haryono, E., & Adityani, R. (2023). The Effect of X-Ray Radiation to IL-10 Levels in Secretome Mesenchymal Stem Cells Cosmeceutical Product. International Journal of Cell and Biomedical Science, 2(4), 118-125. https://doi.org/10.59278/cbs.v2i4.27
Section
Articles

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